Recent Publications
DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression.
Wingo AP, Almli LM, Stevens JJ, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, Bradley B, Binder EB, Jin P, Gibson G, Ressler KJ.
Nature Communications. 2015 Dec 3;6:10106. doi: 10.1038/ncomms10106.
Wingo AP, Almli LM, Stevens JJ, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, Bradley B, Binder EB, Jin P, Gibson G, Ressler KJ.
Nature Communications. 2015 Dec 3;6:10106. doi: 10.1038/ncomms10106.
Extinction reverses olfactory fear-conditioned increases in neuron number and glomerular size.
Morrison FG, Dias BG, Ressler KJ.
Proceedings of the National Academy of Sciences. 2015 Oct 13;112(41):12846-51. doi: 10.1073/pnas.1505068112.
Morrison FG, Dias BG, Ressler KJ.
Proceedings of the National Academy of Sciences. 2015 Oct 13;112(41):12846-51. doi: 10.1073/pnas.1505068112.
Voxel-based morphometry predicts shifts in dendritic spine density and morphology with auditory fear conditioning.
Keifer OP Jr, Hurt RC, Gutman DA, Keilholz SD, Gourley SL, Ressler KJ.
Nature Communications. 2015 Jul 7;6:7582. doi: 10.1038/ncomms8582.
Keifer OP Jr, Hurt RC, Gutman DA, Keilholz SD, Gourley SL, Ressler KJ.
Nature Communications. 2015 Jul 7;6:7582. doi: 10.1038/ncomms8582.
Association of CRP genetic variation and CRP level with elevated PTSD symptoms and physiological responses in a civilian population with high levels of trauma.
Michopoulos V, Rothbaum AO, Jovanovic T, Almli LM, Bradley B, Rothbaum BO, Gillespie CF, Ressler KJ.
American Journal of Psychiatry. 2015 Apr;172(4):353-62. doi: 10.1176/appi.ajp.2014.14020263.
Michopoulos V, Rothbaum AO, Jovanovic T, Almli LM, Bradley B, Rothbaum BO, Gillespie CF, Ressler KJ.
American Journal of Psychiatry. 2015 Apr;172(4):353-62. doi: 10.1176/appi.ajp.2014.14020263.
Amygdala-Dependent Fear Memory Consolidation via miR-34a and Notch Signaling.
Dias BG, Goodman JV, Ahluwalia R, Easton AE, Andero R, Ressler KJ.
Neuron. 2014 Aug 20;83(4):906-18. doi: 10.1016/j.neuron.2014.07.019.
Dias BG, Goodman JV, Ahluwalia R, Easton AE, Andero R, Ressler KJ.
Neuron. 2014 Aug 20;83(4):906-18. doi: 10.1016/j.neuron.2014.07.019.
A role for Tac2, NkB, and Nk3 receptor in normal and dysregulated fear memory consolidation.
Andero R, Dias BG, Ressler KJ.
Neuron. 2014 Jul 16;83(2):444-54. doi: 10.1016/j.neuron.2014.05.028.
Andero R, Dias BG, Ressler KJ.
Neuron. 2014 Jul 16;83(2):444-54. doi: 10.1016/j.neuron.2014.05.028.
A randomized, double-blind evaluation of D-cycloserine or alprazolam combined with virtual reality exposure therapy for posttraumatic stress disorder in Iraq and Afghanistan War veterans.
Rothbaum BO, Price M, Jovanovic T, Norrholm SD, Gerardi M, Dunlop B, Davis M, Bradley B, Duncan EJ, Rizzo A, Ressler KJ.
American Journal of Psychiatry. 2014 Jun 1;171(6):640-8. doi: 10.1176/appi.ajp.2014.13121625.
Rothbaum BO, Price M, Jovanovic T, Norrholm SD, Gerardi M, Dunlop B, Davis M, Bradley B, Duncan EJ, Rizzo A, Ressler KJ.
American Journal of Psychiatry. 2014 Jun 1;171(6):640-8. doi: 10.1176/appi.ajp.2014.13121625.
BDNF deletion or TrkB impairment in amygdala inhibits both appetitive and aversive learning.
Heldt SA, Zimmermann K, Parker K, Gaval M, Weinshenker D, Ressler KJ.
The Journal of Neuroscience. 2014 Feb 12;34(7):2444-50. doi: 10.1523/JNEUROSCI.4085-12.2014.
Heldt SA, Zimmermann K, Parker K, Gaval M, Weinshenker D, Ressler KJ.
The Journal of Neuroscience. 2014 Feb 12;34(7):2444-50. doi: 10.1523/JNEUROSCI.4085-12.2014.
PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus.
Stevens JS, Almli LM, Fani N, Gutman DA, Bradley B, Norrholm SD, Reiser E, Ely TD, Dhanani R, Glover EM, Jovanovic T, Ressler KJ.
Proceedings of the National Academy of Sciences. 2014 Feb 25;111(8):3158-63. doi: 10.1073/pnas.1318955111.
Stevens JS, Almli LM, Fani N, Gutman DA, Bradley B, Norrholm SD, Reiser E, Ely TD, Dhanani R, Glover EM, Jovanovic T, Ressler KJ.
Proceedings of the National Academy of Sciences. 2014 Feb 25;111(8):3158-63. doi: 10.1073/pnas.1318955111.
Parental olfactory experience influences behavior and neural structure in subsequent generations.
Dias BG, Ressler KJ.
Nature Neuroscience. 2014 Jan;17(1):89-96. doi: 10.1038/nn.3594.
Dias BG, Ressler KJ.
Nature Neuroscience. 2014 Jan;17(1):89-96. doi: 10.1038/nn.3594.
Angiotensin Type 1 Receptor Inhibition Enhances the Extinction of Fear Memory.
Marvar PJ, Goodman J, Fuchs S, Choi DC, Banerjee S, Ressler KJ.
Biological Psychiatry. 2013 Oct 3. pii: S0006-3223(13)00777 doi:10.1016/j.biopsych.2013.08.024.
Marvar PJ, Goodman J, Fuchs S, Choi DC, Banerjee S, Ressler KJ.
Biological Psychiatry. 2013 Oct 3. pii: S0006-3223(13)00777 doi:10.1016/j.biopsych.2013.08.024.
Functional evaluation of a PTSD-associated genetic variant: estradiol regulation and ADCYAP1R1.
Mercer KB, Dias B, Shafer D, Maddox SA, Mulle JG, Hu P, Walton J, Ressler KJ.
Translational Psychiatry. 2016 Dec 13;6(12):e978. doi: 10.1038/tp.2016.241. PMID: 27959335
Mercer KB, Dias B, Shafer D, Maddox SA, Mulle JG, Hu P, Walton J, Ressler KJ.
Translational Psychiatry. 2016 Dec 13;6(12):e978. doi: 10.1038/tp.2016.241. PMID: 27959335
Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala.
McCullough K, Choi D, Guo J, Zimmermann K, Walton J, Rainnie D, Ressler KJ.
Nature Communications. 2016 Oct 21;7:13149. doi: 10.1038/ncomms13149. PMID: 27767183
McCullough K, Choi D, Guo J, Zimmermann K, Walton J, Rainnie D, Ressler KJ.
Nature Communications. 2016 Oct 21;7:13149. doi: 10.1038/ncomms13149. PMID: 27767183
Amygdala-Dependent Molecular Mechanisms of the Tac2 Pathway in Fear Learning.
Andero R, Daniel S, Guo JD, Bruner RC, Seth S, Marvar PJ, Rainnie D, Ressler KJ.
Neuropsychopharmacology. 2016 Jun 29. doi: 10.1038/npp.2016.77. [Epub ahead of print] PMID: 27238620
Andero R, Daniel S, Guo JD, Bruner RC, Seth S, Marvar PJ, Rainnie D, Ressler KJ.
Neuropsychopharmacology. 2016 Jun 29. doi: 10.1038/npp.2016.77. [Epub ahead of print] PMID: 27238620
Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and post-traumatic stress disorder.
Kilaru V, Iyer SV, Almli LM, Stevens JS, Lori A, Jovanovic T, Ely TD, Bradley B, Binder EB, Koen N, Stein DJ, Conneely KN, Wingo AP, Smith AK, Ressler KJ.
Translational Psychiatry. 2016 May 24;6:e820. doi: 10.1038/tp.2016.69. PMID: 27219346
Kilaru V, Iyer SV, Almli LM, Stevens JS, Lori A, Jovanovic T, Ely TD, Bradley B, Binder EB, Koen N, Stein DJ, Conneely KN, Wingo AP, Smith AK, Ressler KJ.
Translational Psychiatry. 2016 May 24;6:e820. doi: 10.1038/tp.2016.69. PMID: 27219346
Baseline psychophysiological and cortisol reactivity as a predictor of PTSD treatment outcome in virtual reality exposure therapy.
Norrholm SD, Jovanovic T, Gerardi M, Breazeale KG, Price M, Davis M, Duncan E, Ressler KJ, Bradley B, Rizzo A, Tuerk PW, Rothbaum BO.
Behaviour Research and Therapy. 2016 Jul;82:28-37. doi: 10.1016/j.brat.2016.05.002. Epub 2016 May 7. PMID: 27183343
Norrholm SD, Jovanovic T, Gerardi M, Breazeale KG, Price M, Davis M, Duncan E, Ressler KJ, Bradley B, Rizzo A, Tuerk PW, Rothbaum BO.
Behaviour Research and Therapy. 2016 Jul;82:28-37. doi: 10.1016/j.brat.2016.05.002. Epub 2016 May 7. PMID: 27183343
The Intersection of Environment and the Genome in Posttraumatic Stress Disorder.
Ressler KJ.
JAMA Psychiatry. 2016 Jul 1;73(7):653-4. doi: 10.1001/jamapsychiatry.2016.0349. No abstract available. PMID: 27167446
Ressler KJ.
JAMA Psychiatry. 2016 Jul 1;73(7):653-4. doi: 10.1001/jamapsychiatry.2016.0349. No abstract available. PMID: 27167446
Neuroimaging genetic approaches to Posttraumatic Stress Disorder.
Lebois LA, Wolff JD, Ressler KJ.
Experimental Neurology. 2016 Apr 22. pii: S0014-4886(16)30099-1. doi: 10.1016/j.expneurol.2016.04.019. [Epub ahead of print] Review. PMID: 27109180
Lebois LA, Wolff JD, Ressler KJ.
Experimental Neurology. 2016 Apr 22. pii: S0014-4886(16)30099-1. doi: 10.1016/j.expneurol.2016.04.019. [Epub ahead of print] Review. PMID: 27109180
Early intervention following trauma may mitigate genetic risk for PTSD in civilians: a pilot prospective emergency department study.
Rothbaum BO, Kearns MC, Reiser E, Davis JS, Kerley KA, Rothbaum AO, Mercer KB, Price M, Houry D, Ressler KJ.
Journal of Clinical Psychiatry. 2014 Aug 5. [Epub ahead of print] PubMed PMID: 25188543.
Rothbaum BO, Kearns MC, Reiser E, Davis JS, Kerley KA, Rothbaum AO, Mercer KB, Price M, Houry D, Ressler KJ.
Journal of Clinical Psychiatry. 2014 Aug 5. [Epub ahead of print] PubMed PMID: 25188543.
Interaction between the Cholecystokinin and Endogenous Cannabinoid Systems in Cued Fear Expression and Extinction Retention.
Bowers ME, Ressler KJ.
Neuropsychopharmacology. 2014 Sep 1. doi: 10.1038/npp.2014.225. [Epub ahead of print] PubMed PMID: 25176168.
Bowers ME, Ressler KJ.
Neuropsychopharmacology. 2014 Sep 1. doi: 10.1038/npp.2014.225. [Epub ahead of print] PubMed PMID: 25176168.
Interaction of the ADRB2 Gene Polymorphism With Childhood Trauma in Predicting Adult Symptoms of Posttraumatic Stress Disorder.
Liberzon I, King AP, Ressler KJ, Almli LM, Zhang P, Ma ST, Cohen GH, Tamburrino MB, Calabrese JR, Galea S.
JAMA Psychiatry. 2014 Aug 27. doi: 10.1001/jamapsychiatry.2014.999. [Epub ahead of print] PubMed PMID: 25162199.
Liberzon I, King AP, Ressler KJ, Almli LM, Zhang P, Ma ST, Cohen GH, Tamburrino MB, Calabrese JR, Galea S.
JAMA Psychiatry. 2014 Aug 27. doi: 10.1001/jamapsychiatry.2014.999. [Epub ahead of print] PubMed PMID: 25162199.
An Integrated Neuroscience Perspective on Formulation and Treatment Planning for Posttraumatic Stress Disorder: An Educational Review.
Ross DA, Arbuckle MR, Travis MJ, Dwyer JB, van Schalkwyk GI, Ressler KJ.
JAMA Psychiatry. 2017 Apr 1;74(4):407-415. doi: 10.1001/jamapsychiatry.2016.3325.
Ross DA, Arbuckle MR, Travis MJ, Dwyer JB, van Schalkwyk GI, Ressler KJ.
JAMA Psychiatry. 2017 Apr 1;74(4):407-415. doi: 10.1001/jamapsychiatry.2016.3325.
Gene x Environment Determinants of Stress- and Anxiety-Related Disorders.
Sharma S, Powers A, Bradley B, Ressler KJ.
Annual Review of Psychology. 2016;67:239-61. doi: 10.1146/annurev-psych-122414-033408.
Sharma S, Powers A, Bradley B, Ressler KJ.
Annual Review of Psychology. 2016;67:239-61. doi: 10.1146/annurev-psych-122414-033408.
Neuroimaging Genetic Approaches to Posttraumatic Stress Disorder.
Lebois LAM, Wolff JD, Ressler KJ.
Experimental Neurology. 2016 Oct;284(Pt B):141-152. doi: 10.1016/j.expneurol.2016.04.019.
Lebois LAM, Wolff JD, Ressler KJ.
Experimental Neurology. 2016 Oct;284(Pt B):141-152. doi: 10.1016/j.expneurol.2016.04.019.
The Physiology of Fear: Reconceptualizing the Role of the Central Amygdala in Fear Learning.
Keifer OP Jr, Hurt RC, Ressler KJ, Marvar PJ.
Physiology (Bethesda). 2015 Sep;30(5):389-401. doi: 10.1152/physiol.00058.2014.
Keifer OP Jr, Hurt RC, Ressler KJ, Marvar PJ.
Physiology (Bethesda). 2015 Sep;30(5):389-401. doi: 10.1152/physiol.00058.2014.
Models of Intergenerational and Transgenerational Transmission of Risk for Psychopathology in Mice.
Klengel T, Dias BG, Ressler KJ.
Neuropsychopharmacology. 2016 Jan;41(1):219-31. doi: 10.1038/npp.2015.249
Klengel T, Dias BG, Ressler KJ.
Neuropsychopharmacology. 2016 Jan;41(1):219-31. doi: 10.1038/npp.2015.249
An Overview of Translationally Informed Treatments for Posttraumatic Stress Disorder: Animal Models of Pavlovian Fear Conditioning to Human Clinical Trials.
Bowers ME, Ressler KJ.
Biological Psychiatry. 2015 Sep 1;78(5):E15-27. doi: 10.1016/j.biopsych.2015.06.008.
Bowers ME, Ressler KJ.
Biological Psychiatry. 2015 Sep 1;78(5):E15-27. doi: 10.1016/j.biopsych.2015.06.008.
Mouse models of fear-related disorders: Cell-type-specific manipulations in amygdala.
Gafford GM, Ressler KJ.
Neuroscience. 2015 Jun 20. pii: S0306-4522(15)00550-3. doi: 10.1016/j.neuroscience.2015.06.019.
Gafford GM, Ressler KJ.
Neuroscience. 2015 Jun 20. pii: S0306-4522(15)00550-3. doi: 10.1016/j.neuroscience.2015.06.019.
The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration.
Logue MW, Amstadter AB, Baker DG, Duncan L, Koenen KC, Liberzon I, Miller MW, Morey RA, Nievergelt CM, Ressler KJ, Smith AK, Smoller JW, Stein MB, Sumner JA, Uddin M.
Neuropsychopharmacology. 2015 Sep;40(10):2287-97. doi: 10.1038/npp.2015.118.
Logue MW, Amstadter AB, Baker DG, Duncan L, Koenen KC, Liberzon I, Miller MW, Morey RA, Nievergelt CM, Ressler KJ, Smith AK, Smoller JW, Stein MB, Sumner JA, Uddin M.
Neuropsychopharmacology. 2015 Sep;40(10):2287-97. doi: 10.1038/npp.2015.118.
Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders.
Singewald N, Schmuckermair C, Whittle N, Holmes A, Ressler KJ.
Pharmacology & Therapeutics. 2015 May;149:150-90. doi: 10.1016/j.pharmthera.2014.12.004.
Singewald N, Schmuckermair C, Whittle N, Holmes A, Ressler KJ.
Pharmacology & Therapeutics. 2015 May;149:150-90. doi: 10.1016/j.pharmthera.2014.12.004.
Epigenetic mechanisms underlying learning and the inheritance of learned behaviors.
Dias BG, Maddox SA, Klengel T, Ressler KJ.
Trends in Neurosciences. 2015 Feb;38(2):96-107. doi: 10.1016/j.tins.2014.12.003
Dias BG, Maddox SA, Klengel T, Ressler KJ.
Trends in Neurosciences. 2015 Feb;38(2):96-107. doi: 10.1016/j.tins.2014.12.003
Bridging the Gap: Towards a Cell-Type Specific Understanding of Neural Circuits Underlying Fear Behaviors.
McCullough KM, Morrison FG, Ressler KJ.
Neurobiology of Learning & Memory. 2016 Jul 25. pii: S1074-7427(16)30125-3. doi: 10.1016/j.nlm.2016.07.025
McCullough KM, Morrison FG, Ressler KJ.
Neurobiology of Learning & Memory. 2016 Jul 25. pii: S1074-7427(16)30125-3. doi: 10.1016/j.nlm.2016.07.025
Augmenting Obsessive-Compulsive Disorder Treatment: From Brain to Mind.
Ressler KJ, Rothbaum, BO.
JAMA Psychiatry. 2013 Nov;70(11):1129-1131. doi:10.1001/jamapsychiatry.2013.2116.
Ressler KJ, Rothbaum, BO.
JAMA Psychiatry. 2013 Nov;70(11):1129-1131. doi:10.1001/jamapsychiatry.2013.2116.
.DSM-5 and RDoC: progress in psychiatry research?
Casey BJ, Craddock N, Cuthbert BN, Hyman SE, Lee FS, Ressler KJ.
Nature Reviews Neuroscience. 2013 Nov;14(11):810-4. doi: 10.1038/nrn3621.
Casey BJ, Craddock N, Cuthbert BN, Hyman SE, Lee FS, Ressler KJ.
Nature Reviews Neuroscience. 2013 Nov;14(11):810-4. doi: 10.1038/nrn3621.
Implications of memory modulation for post-traumatic stress and fear disorders.
Parsons RG, Ressler KJ.
Nature Neuroscience. 2013 Feb;16(2):146-53. doi: 10.1038/nn.3296.
Parsons RG, Ressler KJ.
Nature Neuroscience. 2013 Feb;16(2):146-53. doi: 10.1038/nn.3296.
A complete list of publications from the Ressler Lab can be found on ResearchGate or Google Scholar.