Recent Publications
DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression.
Wingo AP, Almli LM, Stevens JJ, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, Bradley B, Binder EB, Jin P, Gibson G, Ressler KJ.
Nature Communications. 2015 Dec 3;6:10106. doi: 10.1038/ncomms10106. PubMed PMID: 26632874; PubMed Central PMCID: PMC4686835.
Wingo AP, Almli LM, Stevens JJ, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, Bradley B, Binder EB, Jin P, Gibson G, Ressler KJ.
Nature Communications. 2015 Dec 3;6:10106. doi: 10.1038/ncomms10106. PubMed PMID: 26632874; PubMed Central PMCID: PMC4686835.
Extinction reverses olfactory fear-conditioned increases in neuron number and glomerular size.
Morrison FG, Dias BG, Ressler KJ.
Proceedings of the National Academy of Sciences. 2015 Oct 13;112(41):12846-51. doi: 10.1073/pnas.1505068112. Epub 2015 Sep 29. PubMed PMID: 26420875; PubMed Central PMCID: PMC4611645.
Morrison FG, Dias BG, Ressler KJ.
Proceedings of the National Academy of Sciences. 2015 Oct 13;112(41):12846-51. doi: 10.1073/pnas.1505068112. Epub 2015 Sep 29. PubMed PMID: 26420875; PubMed Central PMCID: PMC4611645.
Voxel-based morphometry predicts shifts in dendritic spine density and morphology with auditory fear conditioning.
Keifer OP Jr, Hurt RC, Gutman DA, Keilholz SD, Gourley SL, Ressler KJ.
Nature Communications. 2015 Jul 7;6:7582. doi: 10.1038/ncomms8582. PubMed PMID: 26151911; PubMed Central PMCID: PMC4506522.
Keifer OP Jr, Hurt RC, Gutman DA, Keilholz SD, Gourley SL, Ressler KJ.
Nature Communications. 2015 Jul 7;6:7582. doi: 10.1038/ncomms8582. PubMed PMID: 26151911; PubMed Central PMCID: PMC4506522.
Association of CRP genetic variation and CRP level with elevated PTSD symptoms and physiological responses in a civilian population with high levels of trauma.
Michopoulos V, Rothbaum AO, Jovanovic T, Almli LM, Bradley B, Rothbaum BO, Gillespie CF, Ressler KJ.
American Journal of Psychiatry. 2015 Apr;172(4):353-62. doi: 10.1176/appi.ajp.2014.14020263. Epub 2014 Dec 12. PubMed PMID: 25827033; PubMed Central PMCID: PMC4440454.
Michopoulos V, Rothbaum AO, Jovanovic T, Almli LM, Bradley B, Rothbaum BO, Gillespie CF, Ressler KJ.
American Journal of Psychiatry. 2015 Apr;172(4):353-62. doi: 10.1176/appi.ajp.2014.14020263. Epub 2014 Dec 12. PubMed PMID: 25827033; PubMed Central PMCID: PMC4440454.
Amygdala-Dependent Fear Memory Consolidation via miR-34a and Notch Signaling.
Dias BG, Goodman JV, Ahluwalia R, Easton AE, Andero R, Ressler KJ.
Neuron. 2014 Aug 20;83(4):906-18. PubMed Central PMCID: PMC4172484.
Dias BG, Goodman JV, Ahluwalia R, Easton AE, Andero R, Ressler KJ.
Neuron. 2014 Aug 20;83(4):906-18. PubMed Central PMCID: PMC4172484.
A role for Tac2, NkB, and Nk3 receptor in normal and dysregulated fear memory consolidation.
Andero R, Dias BG, Ressler KJ.
Neuron. 2014 Jul 16;83(2):444-54. PubMed Central PMCID: PMC4103970.
Andero R, Dias BG, Ressler KJ.
Neuron. 2014 Jul 16;83(2):444-54. PubMed Central PMCID: PMC4103970.
A randomized, double-blind evaluation of D-cycloserine or alprazolam combined with virtual reality exposure therapy for posttraumatic stress disorder in Iraq and Afghanistan War veterans.
Rothbaum BO, Price M, Jovanovic T, Norrholm SD, Gerardi M, Dunlop B, Davis M, Bradley B, Duncan EJ, Rizzo A, Ressler KJ.
American Journal of Psychiatry. 2014 Jun 1;171(6):640-8. PubMed Central PMCID: PMC4115813.
Rothbaum BO, Price M, Jovanovic T, Norrholm SD, Gerardi M, Dunlop B, Davis M, Bradley B, Duncan EJ, Rizzo A, Ressler KJ.
American Journal of Psychiatry. 2014 Jun 1;171(6):640-8. PubMed Central PMCID: PMC4115813.
BDNF deletion or TrkB impairment in amygdala inhibits both appetitive and aversive learning.
Heldt SA, Zimmermann K, Parker K, Gaval M, Weinshenker D, Ressler KJ.
The Journal of Neuroscience. 2014 Feb 12;34(7):2444-50. doi: 10.1523/JNEUROSCI.4085-12.2014. PubMed Central PMCID: PMC3921419.
Heldt SA, Zimmermann K, Parker K, Gaval M, Weinshenker D, Ressler KJ.
The Journal of Neuroscience. 2014 Feb 12;34(7):2444-50. doi: 10.1523/JNEUROSCI.4085-12.2014. PubMed Central PMCID: PMC3921419.
PACAP receptor gene polymorphism impacts fear responses in the amygdala and hippocampus.
Stevens JS, Almli LM, Fani N, Gutman DA, Bradley B, Norrholm SD, Reiser E, Ely TD, Dhanani R, Glover EM, Jovanovic T, Ressler KJ.
Proceedings of the National Academy of Sciences. 2014 Feb 25;111(8):3158-63. doi: 10.1073/pnas.1318955111. Epub 2014 Feb 10. PubMed PMID 24516127; PubMed central PMCID: PMC3939867.
Stevens JS, Almli LM, Fani N, Gutman DA, Bradley B, Norrholm SD, Reiser E, Ely TD, Dhanani R, Glover EM, Jovanovic T, Ressler KJ.
Proceedings of the National Academy of Sciences. 2014 Feb 25;111(8):3158-63. doi: 10.1073/pnas.1318955111. Epub 2014 Feb 10. PubMed PMID 24516127; PubMed central PMCID: PMC3939867.
Parental olfactory experience influences behavior and neural structure in subsequent generations.
Dias BG, Ressler KJ.
Nature Neuroscience. 2014 Jan;17(1):89-96. doi: 10.1038/nn.3594. Epub 2013 Dec 1. PubMed PMID: 24292232; PubMed Central PMCID: PMC3923835.
Dias BG, Ressler KJ.
Nature Neuroscience. 2014 Jan;17(1):89-96. doi: 10.1038/nn.3594. Epub 2013 Dec 1. PubMed PMID: 24292232; PubMed Central PMCID: PMC3923835.
Angiotensin Type 1 Receptor Inhibition Enhances the Extinction of Fear Memory.
Marvar PJ, Goodman J, Fuchs S, Choi DC, Banerjee S, Ressler KJ.
Biological Psychiatry. 2013 Oct 3. pii: S0006-3223(13)00777- doi:10.1016/j.biopsych.2013.08.024. [Epub ahead of print] PubMed PMID: 24094510.
Marvar PJ, Goodman J, Fuchs S, Choi DC, Banerjee S, Ressler KJ.
Biological Psychiatry. 2013 Oct 3. pii: S0006-3223(13)00777- doi:10.1016/j.biopsych.2013.08.024. [Epub ahead of print] PubMed PMID: 24094510.
Functional evaluation of a PTSD-associated genetic variant: estradiol regulation and ADCYAP1R1.
Mercer KB, Dias B, Shafer D, Maddox SA, Mulle JG, Hu P, Walton J, Ressler KJ.
Translational Psychiatry. 2016 Dec 13;6(12):e978. doi: 10.1038/tp.2016.241. PMID: 27959335
Mercer KB, Dias B, Shafer D, Maddox SA, Mulle JG, Hu P, Walton J, Ressler KJ.
Translational Psychiatry. 2016 Dec 13;6(12):e978. doi: 10.1038/tp.2016.241. PMID: 27959335
Molecular characterization of Thy1 expressing fear-inhibiting neurons within the basolateral amygdala.
McCullough K, Choi D, Guo J, Zimmermann K, Walton J, Rainnie D, Ressler KJ.
Nature Communications. 2016 Oct 21;7:13149. doi: 10.1038/ncomms13149. PMID: 27767183
McCullough K, Choi D, Guo J, Zimmermann K, Walton J, Rainnie D, Ressler KJ.
Nature Communications. 2016 Oct 21;7:13149. doi: 10.1038/ncomms13149. PMID: 27767183
Amygdala-Dependent Molecular Mechanisms of the Tac2 Pathway in Fear Learning.
Andero R, Daniel S, Guo JD, Bruner RC, Seth S, Marvar PJ, Rainnie D, Ressler KJ.
Neuropsychopharmacology. 2016 Jun 29. doi: 10.1038/npp.2016.77. [Epub ahead of print] PMID: 27238620
Andero R, Daniel S, Guo JD, Bruner RC, Seth S, Marvar PJ, Rainnie D, Ressler KJ.
Neuropsychopharmacology. 2016 Jun 29. doi: 10.1038/npp.2016.77. [Epub ahead of print] PMID: 27238620
Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and post-traumatic stress disorder.
Kilaru V, Iyer SV, Almli LM, Stevens JS, Lori A, Jovanovic T, Ely TD, Bradley B, Binder EB, Koen N, Stein DJ, Conneely KN, Wingo AP, Smith AK, Ressler KJ.
Translational Psychiatry. 2016 May 24;6:e820. doi: 10.1038/tp.2016.69. PMID: 27219346
Kilaru V, Iyer SV, Almli LM, Stevens JS, Lori A, Jovanovic T, Ely TD, Bradley B, Binder EB, Koen N, Stein DJ, Conneely KN, Wingo AP, Smith AK, Ressler KJ.
Translational Psychiatry. 2016 May 24;6:e820. doi: 10.1038/tp.2016.69. PMID: 27219346
Baseline psychophysiological and cortisol reactivity as a predictor of PTSD treatment outcome in virtual reality exposure therapy.
Norrholm SD, Jovanovic T, Gerardi M, Breazeale KG, Price M, Davis M, Duncan E, Ressler KJ, Bradley B, Rizzo A, Tuerk PW, Rothbaum BO.
Behaviour Research and Therapy. 2016 Jul;82:28-37. doi: 10.1016/j.brat.2016.05.002. Epub 2016 May 7. PMID: 27183343
Norrholm SD, Jovanovic T, Gerardi M, Breazeale KG, Price M, Davis M, Duncan E, Ressler KJ, Bradley B, Rizzo A, Tuerk PW, Rothbaum BO.
Behaviour Research and Therapy. 2016 Jul;82:28-37. doi: 10.1016/j.brat.2016.05.002. Epub 2016 May 7. PMID: 27183343
The Intersection of Environment and the Genome in Posttraumatic Stress Disorder.
Ressler KJ.
JAMA Psychiatry. 2016 Jul 1;73(7):653-4. doi: 10.1001/jamapsychiatry.2016.0349. No abstract available. PMID: 27167446
Ressler KJ.
JAMA Psychiatry. 2016 Jul 1;73(7):653-4. doi: 10.1001/jamapsychiatry.2016.0349. No abstract available. PMID: 27167446
Neuroimaging genetic approaches to Posttraumatic Stress Disorder.
Lebois LA, Wolff JD, Ressler KJ.
Experimental Neurology. 2016 Apr 22. pii: S0014-4886(16)30099-1. doi: 10.1016/j.expneurol.2016.04.019. [Epub ahead of print] Review. PMID: 27109180
Lebois LA, Wolff JD, Ressler KJ.
Experimental Neurology. 2016 Apr 22. pii: S0014-4886(16)30099-1. doi: 10.1016/j.expneurol.2016.04.019. [Epub ahead of print] Review. PMID: 27109180
Early intervention following trauma may mitigate genetic risk for PTSD in civilians: a pilot prospective emergency department study.
Rothbaum BO, Kearns MC, Reiser E, Davis JS, Kerley KA, Rothbaum AO, Mercer KB, Price M, Houry D, Ressler KJ.
Journal of Clinical Psychiatry. 2014 Aug 5. [Epub ahead of print] PubMed PMID: 25188543.
Rothbaum BO, Kearns MC, Reiser E, Davis JS, Kerley KA, Rothbaum AO, Mercer KB, Price M, Houry D, Ressler KJ.
Journal of Clinical Psychiatry. 2014 Aug 5. [Epub ahead of print] PubMed PMID: 25188543.
Interaction between the Cholecystokinin and Endogenous Cannabinoid Systems in Cued Fear Expression and Extinction Retention.
Bowers ME, Ressler KJ.
Neuropsychopharmacology. 2014 Sep 1. doi: 10.1038/npp.2014.225. [Epub ahead of print] PubMed PMID: 25176168.
Bowers ME, Ressler KJ.
Neuropsychopharmacology. 2014 Sep 1. doi: 10.1038/npp.2014.225. [Epub ahead of print] PubMed PMID: 25176168.
Interaction of the ADRB2 Gene Polymorphism With Childhood Trauma in Predicting Adult Symptoms of Posttraumatic Stress Disorder.
Liberzon I, King AP, Ressler KJ, Almli LM, Zhang P, Ma ST, Cohen GH, Tamburrino MB, Calabrese JR, Galea S.
JAMA Psychiatry. 2014 Aug 27. doi: 10.1001/jamapsychiatry.2014.999. [Epub ahead of print] PubMed PMID: 25162199.
Liberzon I, King AP, Ressler KJ, Almli LM, Zhang P, Ma ST, Cohen GH, Tamburrino MB, Calabrese JR, Galea S.
JAMA Psychiatry. 2014 Aug 27. doi: 10.1001/jamapsychiatry.2014.999. [Epub ahead of print] PubMed PMID: 25162199.
Models of Intergenerational and Transgenerational Transmission of Risk for Psychopathology in Mice.
Klengel T, Dias BG, Ressler KJ.
Neuropsychopharmacology. 2016 Jan;41(1):219-31. doi: 10.1038/npp.2015.249. Epub 2015 Aug 18. PubMed PMID: 26283147; PubMed Central PMCID: PMC4677139.
Klengel T, Dias BG, Ressler KJ.
Neuropsychopharmacology. 2016 Jan;41(1):219-31. doi: 10.1038/npp.2015.249. Epub 2015 Aug 18. PubMed PMID: 26283147; PubMed Central PMCID: PMC4677139.
Bridging the Gap: Towards a Cell-Type Specific Understanding of Neural Circuits Underlying Fear Behaviors.
McCullough KM, Morrison FG, Ressler KJ.
Neurobiology of Learning & Memory. 2016 Jul 25. pii: S1074-7427(16)30125-3. doi: 10.1016/j.nlm.2016.07.025. PMID: 27470092
McCullough KM, Morrison FG, Ressler KJ.
Neurobiology of Learning & Memory. 2016 Jul 25. pii: S1074-7427(16)30125-3. doi: 10.1016/j.nlm.2016.07.025. PMID: 27470092
The Physiology of Fear:Reconceptualizing the Role of the Central Amygdala in Fear Learning.
Keifer OP Jr, Hurt RC, Ressler KJ, Marvar PJ.
Physiology (Bethesda). 2015 Sep;30(5):389-401. doi: 10.1152/physiol.00058.2014. Review. PubMed PMID: 26328883; PubMed Central PMCID: PMC4556826.
Keifer OP Jr, Hurt RC, Ressler KJ, Marvar PJ.
Physiology (Bethesda). 2015 Sep;30(5):389-401. doi: 10.1152/physiol.00058.2014. Review. PubMed PMID: 26328883; PubMed Central PMCID: PMC4556826.
An Overview of Translationally Informed Treatments for Posttraumatic Stress Disorder: Animal Models of Pavlovian Fear Conditioning to Human Clinical Trials.
Bowers ME, Ressler KJ.
Biological Psychiatry. 2015 Sep 1;78(5):E15-27. doi: 10.1016/j.biopsych.2015.06.008. Epub 2015 Jun 15. Review. PubMed PMID: 26238379; PubMed Central PMCID: PMC4527085.
Bowers ME, Ressler KJ.
Biological Psychiatry. 2015 Sep 1;78(5):E15-27. doi: 10.1016/j.biopsych.2015.06.008. Epub 2015 Jun 15. Review. PubMed PMID: 26238379; PubMed Central PMCID: PMC4527085.
Mouse models of fear-related disorders: Cell-type-specific manipulations in amygdala.
Gafford GM, Ressler KJ.
Neuroscience. 2015 Jun 20. pii: S0306-4522(15)00550-3. doi: 10.1016/j.neuroscience.2015.06.019. [Epub ahead of print] Review. PubMed PMID: 26102004; PubMed Central PMCID: PMC4685028.
Gafford GM, Ressler KJ.
Neuroscience. 2015 Jun 20. pii: S0306-4522(15)00550-3. doi: 10.1016/j.neuroscience.2015.06.019. [Epub ahead of print] Review. PubMed PMID: 26102004; PubMed Central PMCID: PMC4685028.
The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration.
Logue MW, Amstadter AB, Baker DG, Duncan L, Koenen KC, Liberzon I, Miller MW,
Morey RA, Nievergelt CM, Ressler KJ, Smith AK, Smoller JW, Stein MB, Sumner JA,
Uddin M.
Neuropsychopharmacology. 2015 Sep;40(10):2287-97. doi: 10.1038/npp.2015.118. Epub 2015 Apr 23. Review. PubMed PMID: 25904361; PubMed Central PMCID: PMC4538342.
Logue MW, Amstadter AB, Baker DG, Duncan L, Koenen KC, Liberzon I, Miller MW,
Morey RA, Nievergelt CM, Ressler KJ, Smith AK, Smoller JW, Stein MB, Sumner JA,
Uddin M.
Neuropsychopharmacology. 2015 Sep;40(10):2287-97. doi: 10.1038/npp.2015.118. Epub 2015 Apr 23. Review. PubMed PMID: 25904361; PubMed Central PMCID: PMC4538342.
Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders.
Singewald N, Schmuckermair C, Whittle N, Holmes A, Ressler KJ.
Pharmacology & Therapeutics. 2015 May;149:150-90. doi: 10.1016/j.pharmthera.2014.12.004. Epub 2014 Dec 27. Review. PubMed PMID: 25550231; PubMed Central PMCID: PMC4380664.
Singewald N, Schmuckermair C, Whittle N, Holmes A, Ressler KJ.
Pharmacology & Therapeutics. 2015 May;149:150-90. doi: 10.1016/j.pharmthera.2014.12.004. Epub 2014 Dec 27. Review. PubMed PMID: 25550231; PubMed Central PMCID: PMC4380664.
Epigenetic mechanisms underlying learning and the inheritance of learned behaviors.
Dias BG, Maddox SA, Klengel T, Ressler KJ.
Trends in Neurosciences. 2015 Feb;38(2):96-107. doi: 10.1016/j.tins.2014.12.003. Epub 2014 Dec 24. Review. PubMed PMID: 25544352; PubMed Central PMCID: PMC4323865.
Dias BG, Maddox SA, Klengel T, Ressler KJ.
Trends in Neurosciences. 2015 Feb;38(2):96-107. doi: 10.1016/j.tins.2014.12.003. Epub 2014 Dec 24. Review. PubMed PMID: 25544352; PubMed Central PMCID: PMC4323865.
Implications of memory modulation for post-traumatic stress and fear disorders.
Parsons RG, Ressler KJ.
Nature Neuroscience. 2013 Feb;16(2):146-53. doi: 10.1038/nn.3296. Epub 2013 Jan 28. Review. PubMed PMID: 23354388; PubMed Central PMCID: PMC3752300.
Parsons RG, Ressler KJ.
Nature Neuroscience. 2013 Feb;16(2):146-53. doi: 10.1038/nn.3296. Epub 2013 Jan 28. Review. PubMed PMID: 23354388; PubMed Central PMCID: PMC3752300.
DSM-5 and RDoC: progress in psychiatry research?
Casey BJ, Craddock N, Cuthbert BN, Hyman SE, Lee FS, Ressler KJ.
Nature Reviews Neuroscience. 2013 Nov;14(11):810-4. doi: 10.1038/nrn3621. Review. PubMed PMID: 24135697; PubMed Central PMCID: PMC4372467.
Casey BJ, Craddock N, Cuthbert BN, Hyman SE, Lee FS, Ressler KJ.
Nature Reviews Neuroscience. 2013 Nov;14(11):810-4. doi: 10.1038/nrn3621. Review. PubMed PMID: 24135697; PubMed Central PMCID: PMC4372467.
A complete list of publications from the Ressler Lab can be found on ResearchGate or Google Scholar.
